4 Andro Review: Benefits, Results, Side Effects, & More

Testosterone exists at the heart of muscle growth.

Consequently, it’s crucial to monitor testosterone levels if you need to lose weight and gain lean muscle.

Nevertheless, the ordinary person does not have access to advance technology or dietitians like professional bodybuilders.

As a result, muscle growth supplements like 4 Andro are often the answer to solving issues related to body image.

These prohormones convert 4-DHEA to Androstenedione and Androstenediol which, subsequently, converts to testosterone.1

Thus, users feel more empowered, invigorated, and healthier.

Learn more about the prohormone capsule in our complete 4 Andro review:

What Is 4 Andro?

1 andro is one of the best prohormones for strength and mass

Note: Click Here to buy 4-Andro legally from our #1 rated source, Pure Rawz.

4 Andro (short for 4-androsterone) is a non-liver toxic anabolic prohormone supplement.

The muscle growth supplement contains 4-Dehydroepiandrosterone (4-DHEA).

4-DHEA is vital to testosterone production in the body and is therefore known to improve athletic function.2

Thus, users that supplement 4 Andro report several benefits:

  • Lean Muscle Growth
  • Improved Sex Drive
  • Higher Sleep Quality
  • Improved Energy & Focus
  • Stronger Appetite
  • Improved Self-Esteem

For this reason, 4 Andro is capable of improving lean muscle, fatigue, focus, and recovery.

Additionally, users notice a stronger sense of self-esteem including improved confidence, motivation, and libido.

It’s traditionally regarded as a “wet” compound.

In turn, it’s more practical for bulking cycles compared to cycles necessary for cutting weight.

How Does 4 Andro Work?

4 Andro is a supplement that is utilized by some bodybuilders and athletes for its muscle-building properties.

The primary ingredient of 4 Andro is 4-Dehydroepiandrosterone (4-DHEA).

4-DHEA acts as the positional isomer and its chemical structural modification reduce the potential for extreme calorie burning.

Meanwhile, the androgenic properties and nitric oxide synthesis are increased thanks to its ability to bind to human muscular receptors.

In other words, some may compare it to anabolic steroids yet the side effects are considered far less severe (more information, below).

In general, it’s more similar to the chemical structure of testosterone compared to 1-androsterone (1 Andro).

It also serves as a weak potential agonist of the androgen receptor.

In consequence, the substance does not demonstrate an affinity for binding the prominent androgen receptor.

However, as a prohormone, it converts to testosterone thanks to the enzyme 3-beta hydroxysteroid dehydrogenase (3bHSD).

While the bioavailability is rather poor, it’s still viewed better compared to that of 1-Androstenedione.

Moreover, the half-life of 4 Andro is relatively short.

In accordance, large and frequent doses are required to notice results (more information, below).

4 Andro Side Effects

4 Andro (4-DHEA) is a precursor to human steroid hormones.

Consequently, it converts to testosterone (like anabolic steroids) yet does not produce nearly the same horrible side effects.3

Moreover, it converts testosterone faster compared to traditional DHEA supplements.4

The side effects of 4 Andro are largely viewed as mild to moderate.

There is potential for the substance to convert to either DHT or estrogen.

However, the risks and side effects are not considered nearly as damaging:

  • Acne
  • Hair Loss
  • Mood Shifts

Additionally, 4 Andro use may suppress the natural level of testosterone production.

However, many of these side effects are manageable thanks to the use of an aromatase inhibitor (AI).

Regardless, since it’s non-methylated, stress on the liver is not evident.

Users may limit the side effects by following Post Cycle Therapy (PCT).

Post Cycle Therapy is often necessary to reduce estrogen conversion as well as restore the natural rate of testosterone production.

Prohormones like 4 Andro typically benefit young male athletes that are 21 and older.

In general, testosterone levels begin to decline with age which makes supplementation so crucial.

4 Andro Review: Does It Really Work?

The controversy over 4 Andro and other prohormones remain problematic.5

While many athletes and bodybuilders support its supplementation, it is not endorsed by the FDA.

Despite the limitations, it remains one of the fastest and least harmful methods to produce lean muscle.

It allows you to lose excess weight, gain muscle, and witness better focus and memory.

Moreover, 4 Andro and other prohormones are not known to produce the same harmful side effects as traditional anabolic steroids.

It’s a synthetic non-methylated prohormone which means it does not damage the liver.

Additionally, many often stack it with its fellow cousin – 1 Andro.

Those that stack 4 Andro with 1 Andro should also shop for other supplement options in order to maintain healthy hormonal ratios.

Those that begin supplementing 4-DHEA should understand the potential risks of the compound.6

Lastly, starting at lower doses can help offset the potential side effects.

How To Use It

4 Andro is a prohormone that is generally available in liquid or capsule form.

Its purpose is to counter an imbalance of testosterone by converting 4-DHEA to androstenedione or androstenediol.

It’s suggested that new users introduce 4 Andro to their daily regime with a cycle that lasts between 6-8 weeks.

Please note that the cycle should include Post Cycle Therapy (PCT) as well as a break from 4 Andro (comparable to the length of the cycle).

New users should stick to a recommended daily dose of 200-400mg.

The ideal consumption method is to split the daily intake into two separate, equal doses.

For this reason, most bodybuilders supplement once in the morning and once in the afternoon.

However, those that are using it as part of a weight stack may want to reduce the daily intake, especially when consuming with 1 Andro.

Those that are experienced with it may consume as much as 1,000mg daily, divided into 3 separate doses.

The short half-life produces immediate results and is why many use right before a workout session.

Furthermore, some experts recommend taking 4 Andro with a fatty meal since the prohormone is non-methylated and demonstrates poor bioavailability.7

While it can significantly impact lean muscle growth and overall performance, do not take longer than suggested cycles.

4 Andro remains unregulated by the FDA and questions remain about its long-term use.

Where Can You Buy 4 Andro?

4 Andro is available from reputable suppliers such as Pure Rawz, click here to see their page on it.

The supplier offers affordable prices on prohormones as well as free shipping.

Moreover, the money-back guarantee ensures that you’ll have the time and patience to try out a new supplement for your weight stack.

The capsules available from Pure Rawz are available in the 50mg individual serving/60 count supply for under $100.

They also sell a liquid version for around the same price, visit their website at the following link to learn more:

Pure Rawz ships all of their prohormones in air-sealed mylar bags.

The manufacturer advises sealing and storing it in a cool, dry place.

Finally, customer satisfaction is the number one priority of Pure Rawz.

1 Andro vs. 4 Andro

4 Andro is often stacked with 1 Andro.

Consequently, many ask what is the primary difference between the two prohormones?

In general, 1 Andro features the naturally occurring DHEA isomer.

1-DHEA converts to 1-androstenediol or testosterone, compared to estrogen (like typical anabolic steroids).

As a result, it is the ideal complement to muscle-building supplements like 1 Andro.

The two prohormones both influence lean muscle growth yet at different rates.

Bodybuilders generally agree that 4 Andro is more suitable for achieving fast muscle and strength gains.

Meanwhile, this boost in testosterone also does not come with the unfortunate side effect of increased DHT and estrogen levels.

All in all, stacking 4 Andro and 1 Andro together enables users to achieve fitness goals during both dry and wet lean muscle cycles.

The below Youtube video from user ‘Sam Stolt’ does a pretty good job of breaking it all down:

Lastly, it stacks well with many other Selective Androgen Receptor Modulators (SARMS).

RAD-140 Testolone, Phenibut HCL, and Amino Tadalafil are all popular stacking options.


4 Andro is one of the premier prohormones.

The compound assists with converting 4-DHEA to testosterone.

Testosterone is crucial to gaining lean muscle and supporting fitness goals.

As a result, it delivers improved strength, focus, stamina, and recovery.

The prohormone compound stacks well with a variety of other prohormones and Selective Androgen Receptor Modulators (SARMs).

It’s an important ingredient to your daily regime and workout cycle.

It presents explosive power, energy, and mental aggression for witnessing a body composition overhaul.

All in all, it’s worthy of giving it a shot.


  1. Ziegenfuss TN, Berardi JM, Lowery LM. Effects of prohormone supplementation in humans: a review. Can J Appl Physiol. 2002;27(6):628-646. doi:10.1139/h02-037 (source)
  2. Morales AJ, Haubrich RH, Hwang JY, Asakura H, Yen SS. The effect of six months treatment with a 100 mg daily dose of dehydroepiandrosterone (DHEA) on circulating sex steroids, body composition and muscle strength in age-advanced men and women. Clin Endocrinol (Oxf). 1998;49(4):421-432. doi:10.1046/j.1365-2265.1998.00507.x (source)
  3. Broeder CE. Oral andro-related prohormone supplementation: do the potential risks outweigh the benefits?. Can J Appl Physiol. 2003;28(1):102-116. doi:10.1139/h03-009 (source)
  4. Inaba M, Nakao T. Conversion of 4-androstenediol and 5-androstenediol to testosterone, and conversion of dehydroepiandrosterone to 4-androstenediol by rat testis in vitro. Endocrinol Jpn. 1966;13(2):160-172. doi:10.1507/endocrj1954.13.160 (source)
  5. Badawy MT, Sobeh M, Xiao J, Farag MA. Androstenedione (a Natural Steroid and a Drug Supplement): A Comprehensive Review of Its Consumption, Metabolism, Health Effects, and Toxicity with Sex Differences. Molecules. 2021;26(20):6210. Published 2021 Oct 14. doi:10.3390/molecules26206210 (source)
  6. Uralets VP, Gillette PA. Over-the-counter delta5 anabolic steroids 5-androsen-3,17-dione; 5-androsten-3beta, 17beta-diol; dehydroepiandrosterone; and 19-nor-5-androsten-3,17-dione: excretion studies in men. J Anal Toxicol. 2000;24(3):188-193. doi:10.1093/jat/24.3.188 (source)
  7. National Center for Biotechnology Information. PubChem Compound Summary for CID 136297, 4-Androstenediol.  Accessed May 13, 2022. (source)

See Also 

MOTS-C Review: 10 BIG Benefits Of This Peptide

HGH Fragment 176-191 Review

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TB-500 Peptide Review

Paul Musumba
4 Andro

4 Andro

4.5 out of 5 (61 Ratings)

4 Andro is a prohormone that claims many benefits, but does it really work? Read our review to learn more about the side effects, dose, before and after results, and more.

By Paul Musumba

Paul Musumba has been an organic chemistry instructor for CHAD Phila since December of 2017. Prior to his stint at CHAD, he was a chemistry teacher at Delaware Valley Charter High School in Philadelphia. He received a B.S. in Biology and Organic Chemistry from Drexel University in 2010, and a masters degree in Chemistry and Computer Science with Teaching, Organic and computational Chemistry from Temple University in 2016. You can read more about Paul's experience and publications on his LinkedIn profile here:

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