GHRP-2 Peptide Review: Dosage, Side Effects, Results, & More

Peptides are natural parts of the human body, but lab-made peptides often find their way into different types of supplements.

This is because the peptides have the potential to provide a wide range of benefits including help with building muscles.

Below, we’ll be learning more about GHRP-2 to get a better idea of what this peptide can do, who might want to consider taking it, and how they should take it.

What Is GHRP-2?

ghrp-2 benefits

Note: Click Here to pick up GHRP-2 legally from our #1 source, Core Peptides.

GHRP stands for growth hormone-releasing peptides, and have been used for a long time and for a host of reasons.1

They have been used to help those who have a growth hormone deficiency, as well as those who are trying to increase their muscle mass, such as bodybuilders.2

It is a synthetic chain of six amino acids, and it helps your body to release more growth hormone.3

The other name for GHRP-2 is pralmorelin.4

It was the first of the growth hormone-releasing peptides to be introduced to clinical settings, and it has been investigated for a range of purposes.

It could provide a host of different types of benefits for users, specifically men suffering from low libido issues.5

Naturally, one of the main reasons people use GHRP-2 is because it has the potential to increase the amount of lean muscle mass.6

It promotes muscle growth along with strength and performance.7

Naturally, this is the type of supplement that will appeal to bodybuilders or anyone who wants to put on muscle.

However, there are other benefits to be had from GHRP-2, as well. Because of the way it works, it could help with anti-aging.

It may improve overall regeneration of the body, keeping you looking and feeling younger for longer.

In addition to the anti-aging and rejuvenating effects, it can support fat burning, helping you to look leaner.8

The use of the GHRP-2 can help to improve collagen production, allowing you to have healthier-looking skin.

It could also boost your immune system and help to reduce the risk of cardiovascular disease.

One of the reasons that some are using the GHRP-2 is to help with healing after injuries.

Whether you are older, or you are young and have an injury that’s not healing as quickly as you would like, this peptide could be a good solution.

The growth hormone that’s released could help your body to repair itself far faster than it could with normal healing.

As you can see, there are many reasons to consider using this peptide beyond just trying to increase strength and muscle mass.

How Does GHRP-2 Work?

This peptide sends out signals to your pituitary gland.

It lets the gland know that the production of growth hormone needs to be increased. However, that’s not all that the peptide does.

It will also suppress a hormone called somatostatin, which is found in the endocrine system.

This hormone typically inhibits the production of growth hormone.

By essentially suppressing this, it means that the increase in growth hormone will be greater.

Typically, someone will receive between one and three applications of the peptide per day.

You will find that this is a fast-acting and powerful peptide that goes to work almost immediately.

After the injection, it is absorbed and starts working within minutes in many cases.

Once you start taking it regularly, you should see some good and continued results over the weeks.

Depending on your dosages, you could see antiaging effects and you could even feel more youthful.

Those who take higher dosages will start to notice increases in strength and the size of their muscles.

When you are dosing, make sure you know what you want to achieve from the GHRP-2.

Side Effects of GHRP-2

Like other peptides and other supplements, there is always the potential for adverse side effects occurring.

However, you will be happy to know that for the most part, the side effects associated with GHRP-2 tend not to be too serious.

One of the first issues that some people might have is increased water retention.

This usually occurs in the first two weeks of taking the peptide.

Because of the additional water being retained in the body, it could cause some to feel pain or tingling in their shoulders, as the water could press some nerves.

It could also cause the hands to feel somewhat numb.

Typically, those symptoms are going to be gone within the first 10 to 14 days after use.

In some people, there could also be skin irritation that occurs at the injection site.

Some who have taken the GHRP-2 have complained about dizziness, but this is very rare.

This peptide does not affect the endocrine system.

However, when the doses are too high, could increase prolactin levels.

This could then increase the chance of prolactin causing gynecomastia in those who are sensitive.

One of the interesting effects that have been seen with some who take the peptide is an increase in hunger.

This means that there could be the temptation to start eating a bit more than usual.

It tends to be worse with GHRP-6 than it is with GHRP-2, but it can still happen.

If you notice that you have a bigger appetite and want to eat more, be careful of what you are putting into your body.

Make sure it’s good and healthy food that will be conducive to helping you put on healthy muscle.

You don’t want to start eating unhealthily, as you might put on more fat weight when you are trying to build muscle.

Many users can ignore the added hunger.

As long as they are eating enough healthy calories for the day, they don’t find it to be too bad.

Other than these effects, there aren’t really any worries that come from taking the peptide.

As long as you are taking proper dosages and you don’t stay on it for more than 16 weeks at a time, you shouldn’t have any issues.

If you do, make sure you stop immediately.

Does GHRP-2 Really Work?

Naturally, you want to make sure that you know whether the product you are considering even works.

Fortunately, you will find an overwhelming number of positive reviews around the web from people who have used GHRP-2.

One of the best places to find reviews from people who have used the product is through YouTube.

A lot of channels, such as Big Tex Gym, talk about GHRP-2 and other peptides.

They discuss what it’s like to take them, the feelings you can expect, and how it works overall.

Dr. Kwaz from the Peptide Knowledge channel has a video talking about GHRP-2, as well.

What you will find whether you check out the videos on YouTube or scour subreddits trying to find information is that it works.

These are amino acids and peptides, and we know that they work in the body for a host of different purposes.

As long as you are dosing properly, you can expect to see some great results.

Of course, you also need to be sure you have high-quality GHRP-2.

How to Use GHRP-2

First, you need to know how to reconstitute and maintain the peptides.

Typically, they are provided in a lyophilized compound, which means that they have been turned into a crystalline powder.

Before you can use them and inject them, you need to add fluid to them and reconstitute them.

It is important to ensure that this is done correctly.

You will need to have an alcohol wipe, a syringe, the peptide, and sterile water or bacteriostatic water.

Start by wiping down the top of the files with an alcohol wipe.

This is a safety precaution to ensure that no outside elements are introduced.

Then, you will use a syringe to pull the liquid from its vial, ensuring you don’t contaminate the needle in the process.

Add the liquid to the peptide container to reconstitute. The amount of liquid you add will vary based on the size of the container.

The GHRP-2 bottles are typically either 5 mg or 10 mg.

You can use 2 ml of water for a 5 mg bottle and 4 ml of water for a 10 mg bottle.

This will ensure that the doses you take will be the same—100mcg or 0.1 mg.

This will equal two ticks on an insulin syringe.

When you add the water, don’t just squirt it down into the vial, as this could damage the peptides and make them useless.

Instead, you want to slowly drip the water down the side of the vial.

This will allow for reconstitution without destroying the peptides.

Additionally, you don’t want to shake up the vial or drop it, as it can damage the peptides, as well.

When you are using GHRP-2, the mode of administration is to inject it subcutaneously into a fleshy part of the body.

Most of the time, this is going to be in the abdominal area.

Of course, there are other options for GHRP-2 that can be taken through nasal sprays or orally.

Once you have reconstituted the injectable solution, you can keep it in the refrigerator. It should stay good for up to 30 days.

Those who are going to be using the GHRP-2 for gaining strength can take a dose of about 300 mcg or 0.3 mg per dose, administered at 100 mcg three times per day.

Those who are only looking for the anti-aging benefits will not need to have as high of a dose.

They could choose 150 mcg or 0.15 mg per dose.

It’s recommended that you do not eat for at least one hour before you use GHRP-2.

Something that you might want to keep in mind is that best dosages can vary by body composition.

Therefore, you might want to start with the lower doses and then start to increase them to get the results that you hope to achieve.

Just make sure you aren’t going beyond the recommended 300 mcg per dose.

How long should you continue taking GHRP-2?

Typically, a user will want to cycle the use of this peptide. They will want to stick to cycles of 12 to 16 weeks max.

They should then take a break before going on another cycle.

Where Can You Buy GHRP-2?

If you are interested in purchasing GHRP-2, make sure you are buying from a quality company that can provide you with the best quality.

We personally recommend the Core Peptides brand, click here to see their page on GHRP-2.

When you buy through the site, you have options when it comes to the size. You could opt for either the 5 mg or the 10 mg bottle.

Buying the larger bottle will help you to save some money.

Another way to save on the cost is to buy more than $100 worth of products from the store at once.

This will ensure that you have free shipping.

The site offers a secure checkout, and you can be sure you are getting a quality product.

The site also offers a 100% satisfaction guarantee.

Buying online through a reputable seller is the easiest way to get your hands on great peptides.

Be sure to check out some of the other supplement options available on their website, as well.

Here’s a link to their full lineup on peptides:


Now that you have a better understanding of what this manmade peptide is all about, you can see why so many other people have become interested in using it.

There are some great benefits for those who are looking for an anti-aging product, but the real magic tends to be for those who are looking to increase their muscle mass.

If you are thinking about the product, make sure you understand how to reconstitute it properly, how to inject it, and how to make the most of it.

This is a relatively affordable option for a supplement that works as well as it does.

You need to be sure that you don’t ruin the peptides when you reconstitute it though, or else you could be wasting money.

A little research, watching some videos, and taking your time will ensure you don’t make those costly mistakes.


  1. Berlanga-Acosta J, Abreu-Cruz A, Herrera DGB, et al. Synthetic Growth Hormone-Releasing Peptides (GHRPs): A Historical Appraisal of the Evidences Supporting Their Cytoprotective Effects. Clin Med Insights Cardiol. 2017;11:1179546817694558. Published 2017 Mar 2. doi:10.1177/1179546817694558 (source)
  2. Chihara K, Shimatsu A, Hizuka N, et al. A simple diagnostic test using GH-releasing peptide-2 in adult GH deficiency. Eur J Endocrinol. 2007;157(1):19-27. doi:10.1530/EJE-07-0066 (source)
  3. Chen C, Pullar M, Loneragan K, Zhang J, Clarke IJ. Effect of growth hormone-releasing peptide-2 (GHRP-2) and GH-releasing hormone (GHRH) on the the cAMP levels and GH release from cultured acromegalic tumours. J Neuroendocrinol. 1998;10(6):473-480. doi:10.1046/j.1365-2826.1998.00233.x (source)
  4. Pralmorelin: GHRP 2, GPA 748, growth hormone-releasing peptide 2, KP-102 D, KP-102 LN, KP-102D, KP-102LN. Drugs R D. 2004;5(4):236-239. doi:10.2165/00126839-200405040-00011 (source)
  5. Veldhuis JD, Keenan DM, Bailey JN, Miles JM, Bowers CY. Preservation of GHRH and GH-releasing peptide-2 efficacy in young men with experimentally induced hypogonadism. Eur J Endocrinol. 2009;161(2):293-300. doi:10.1530/EJE-09-0270 (source)
  6. Phung LT, Inoue H, Nou V, et al. The effects of growth hormone-releasing peptide-2 (GHRP-2) on the release of growth hormone and growth performance in swine. Domest Anim Endocrinol. 2000;18(3):279-291. doi:10.1016/s0739-7240(00)00050-3 (source)
  7. Hu R, Wang Z, Peng Q, et al. Effects of GHRP-2 and Cysteamine Administration on Growth Performance, Somatotropic Axis Hormone and Muscle Protein Deposition in Yaks (Bos grunniens) with Growth Retardation. PLoS One. 2016;11(2):e0149461. Published 2016 Feb 19. doi:10.1371/journal.pone.0149461 (source)
  8. Roh SG, He ML, Matsunaga N, Hidaka S, Hidari H. Mechanisms of action of growth hormone-releasing peptide-2 in bovine pituitary cells. J Anim Sci. 1997 Oct;75(10):2744-8. doi: 10.2527/1997.75102744x. PMID: 9331879. (source)

See Also

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PT-141 Peptide Review: 8 Big Benefits For Men & Women

Epitalon Review: Dose, Before & After Results, & Benefits

MOTS-C Review: 10 BIG Benefits Of This Peptide

Paul Musumba


4.8 out of 5 (77 Ratings)

Our GHRP 2 review discusses everything you need to know about this peptide, including user before and after results, side effects, dose, and more.

By Paul Musumba

Paul Musumba has been an organic chemistry instructor for CHAD Phila since December of 2017. Prior to his stint at CHAD, he was a chemistry teacher at Delaware Valley Charter High School in Philadelphia. He received a B.S. in Biology and Organic Chemistry from Drexel University in 2010, and a masters degree in Chemistry and Computer Science with Teaching, Organic and computational Chemistry from Temple University in 2016. You can read more about Paul's experience and publications on his LinkedIn profile here:

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